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Valrubicin is a semisynthetic analog from the anthracycline doxorubicin, which could influence various interrelated biological features, nearly all of which happen to be involved in nucleic acid metabolism. The drug is administered specifically in the bladder with the therapy of bladder most cancers.
Daunorubicin interacts with DNA by intercalation and inhibition of macromolecular biosynthesis. This inhibits the development of your enzyme topoisomerase II, which relaxes supercoils in DNA for transcription.
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Epirubicin is favoured about doxorubicin, the most popular anthracycline, in a few chemotherapy regimens mainly because it seems to cause much less Unintended effects. In 1999 epirubicin acquired FDA acceptance as being a part of adjuvant therapy in node-good patients.